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Adenomyosis—A Call for Awareness, Early Detection, and Effective Treatment Strategies: A Narrative Review.
- Source :
- Healthcare (2227-9032); Aug2024, Vol. 12 Issue 16, p1641, 8p
- Publication Year :
- 2024
-
Abstract
- Objective: To provide a brief summary of the high incidence, symptomatology, different types, and diagnosis of adenomyosis and to explore various aspects of the disease, with the primary aim of raising awareness among gynecologists for appropriate and early detection. Background: Adenomyosis, a benign gynecological condition characterized by the infiltration of endometrial tissue into the myometrium, poses significant challenges to women's reproductive health. Methods: A narrative review was conducted by searching PubMed, Scopus, and Cochrane databases and offering a non-systematic summary and critical analysis of current knowledge on the impact of adenomyosis on women's health. Articles published in the English language up to May 2023, including original scientific papers, clinical trials, meta-analyses, and reviews focusing on various aspects of adenomyosis, were included in the synthesis of this review. Conclusions: Approximately 20% of women are affected by adenomyosis, which manifests with various subtypes, distinct epidemiological profiles, symptomatology, and treatment responses. Despite its clinical significance, adenomyosis remains understudied, resulting in a significant disparity in research and the literature compared to other gynecological conditions. The severity of adenomyosis is compounded when coexisting with endometriosis, particularly deep-infiltrating endometriosis (DIE), leading to exacerbated fertility issues and severe symptomatology. The wide range of symptoms, including adverse pregnancy outcomes such as pre-eclampsia, highlights its wider impact and emphasizes the need for increased awareness of the condition. Adenomyosis is frequently associated with treatment failure in endometriosis, contributing to dienogest resistance, elevated discontinuation rates, and persistent pain post-endometriosis surgery. Additionally, the lack of specific treatments tailored to adenomyosis poses a considerable challenge in clinical management. [ABSTRACT FROM AUTHOR]
- Subjects :
- DIAGNOSIS of endometriosis
TREATMENT of endometriosis
REPRODUCTIVE health
POSTOPERATIVE pain
INFERTILITY
SEVERITY of illness index
PREGNANCY outcomes
MINIMALLY invasive procedures
ENDOMETRIOSIS
PREECLAMPSIA
MEDICAL research
MEDICAL literature
EARLY diagnosis
GYNECOLOGISTS
TREATMENT failure
DISEASE complications
SYMPTOMS
Subjects
Details
- Language :
- English
- ISSN :
- 22279032
- Volume :
- 12
- Issue :
- 16
- Database :
- Complementary Index
- Journal :
- Healthcare (2227-9032)
- Publication Type :
- Academic Journal
- Accession number :
- 179382378
- Full Text :
- https://doi.org/10.3390/healthcare12161641