Data from Pune Update Knowledge in HIV/AIDS (ROS Chronicles in HIV Infection: Genesis of Oxidative Stress, Associated Pathologies, and Therapeutic Strategies).

A recent report published in AIDS Weekly discusses the role of reactive oxygen species (ROS) in HIV infection and the associated pathologies. The study highlights the dual nature of ROS, which can trigger host antiviral responses but also promote viral replication. The research emphasizes the need for further investigation into the multifaceted roles of ROS in HIV pathophysiology and explores potential therapeutic strategies, including antioxidant therapy, to mitigate the toxicities and pathologies associated with antiretroviral therapy-induced oxidative stress. The report provides valuable insights into the mechanisms of ROS generation and their impact on HIV infection and retroviral therapy. [Extracted from the article]