Immunofluorescent Localization of Ca2+ Sensor Proteins in Somatic Motor Muscles of the Earthworm Lumbricus terrestris.

Immunofluorescent labeling revealed calmodulin, Ca²⁺/calmodulin-dependent protein kinases I and II, synaptotagmin II and VII, and calcineurin A in somatic motor muscles of the earthworm Lumbricus terrestris. These Ca²⁺ sensor proteins are detected in both synaptic and extrasynaptic regions. However, synaptotagmin II and VII, as well as calcineurin A, are mainly localized in the area of neuromuscular junctions, with the synaptic localization for synaptotagmin VII and calcineurin A being pronounced most distinctly. [ABSTRACT FROM AUTHOR]