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Generation of an infectious cDNA clone for NADC30-like PRRSV.

Authors :
Yang-Yang Qiao
Hai-Ming Wang
Hui Lu
Yong-Juan Wang
Wei Zhang
Hao Gu
Xue-Hui Cai
Qin-Se Xu
Zhang-Yan Chen
Yan-Dong Tang
Source :
Frontiers in Veterinary Science; 2024, p1-6, 6p
Publication Year :
2024

Abstract

The porcine reproductive and respiratory syndrome virus (PRRSV) is a highly significant infectious disease that poses a substantial threat to the global pig industry. In recent years, the NADC30-like strain has gradually emerged as prevalent in China, causing a profound impact on the country's pig farming industry. Therefore, it is important to conduct an in-depth study on the characteristics and gene functions of the NADC30-like strain. An infectious cDNA clone is an indispensable tool for investigating the functions of viral genes. In this current study, we successfully isolated a NADC30-like strain and constructed its full-length infectious cDNA clone. The utilization of this clone will facilitate our investigation into the viral replication, pathogenesis, and immune response associated with the PRRSV NADC30-like strain. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22971769
Database :
Complementary Index
Journal :
Frontiers in Veterinary Science
Publication Type :
Academic Journal
Accession number :
179309669
Full Text :
https://doi.org/10.3389/fvets.2024.1468981