The crosstalk between N6‐methyladenosine readers and neuroblastoma.

Background: Neuroblastoma (NB) is a heterogeneous pediatric solid tumour strongly influenced by epigenetic modifications. Methods: This review explores the role of N6‐methyladenosine (m6A) modifications and their readers in NB progression. Results: Dysregulation of m6A readers, including YTHDF1/2, YTHDC1, IGF2BP1/2/3, HNRNPA2B1 and HNRNPC, has been associated with susceptibility and progression. Conclusion: Understanding the crosstalk between m6A readers and NB could offer new insights into diagnosis, prognosis, and treatment strategies. [ABSTRACT FROM AUTHOR]