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Smccnet 2.0: a comprehensive tool for multi-omics network inference with shiny visualization.
- Source :
- BMC Bioinformatics; 8/24/2024, Vol. 25 Issue 1, p1-23, 23p
- Publication Year :
- 2024
-
Abstract
- Summary: Sparse multiple canonical correlation network analysis (SmCCNet) is a machine learning technique for integrating omics data along with a variable of interest (e.g., phenotype of complex disease), and reconstructing multi-omics networks that are specific to this variable. We present the second-generation SmCCNet (SmCCNet 2.0) that adeptly integrates single or multiple omics data types along with a quantitative or binary phenotype of interest. In addition, this new package offers a streamlined setup process that can be configured manually or automatically, ensuring a flexible and user-friendly experience. Availability: This package is available in both CRAN: https://cran.r-project.org/web/packages/SmCCNet/index.html and Github: https://github.com/KechrisLab/SmCCNet under the MIT license. The network visualization tool is available at https://smccnet.shinyapps.io/smccnetnetwork/. [ABSTRACT FROM AUTHOR]
- Subjects :
- MULTIOMICS
MACHINE learning
STATISTICAL correlation
PHENOTYPES
Subjects
Details
- Language :
- English
- ISSN :
- 14712105
- Volume :
- 25
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- BMC Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 179231194
- Full Text :
- https://doi.org/10.1186/s12859-024-05900-9