FGFR1 wild-type rosette-forming glioneuronal tumours.

This article presents three cases of rosette-forming glioneuronal tumors (RGNT) that were diagnosed through DNA-methylation profiling. These cases did not exhibit the classical FGFR1 alteration commonly associated with this type of tumor. The article provides detailed descriptions of each case, including patient history, symptoms, MRI findings, histological analysis, and molecular analysis. The study expands the understanding of RGNT by identifying genetic abnormalities other than FGFR1 mutation, which has implications for potential therapeutic interventions. [Extracted from the article]