Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 2).

This document is an update alert from the American College of Physicians (ACP) on nonpharmacologic and pharmacologic treatments for adults with major depressive disorder. The ACP conducted a surveillance search and identified one new study that met the inclusion criteria. However, the new evidence did not change the prior conclusions of the living systematic review. As a result, the ACP decided that an update of the review is not necessary at this time. The ACP reaffirms the recommendations in the living clinical guideline on nonpharmacologic and pharmacologic treatments for major depressive disorder. [Extracted from the article]