Improved ultra-sonochemical synthesis of triazine based pyrazoline derivative using different catalyst.

Synthesis of 1-(4-(4,6-bis(4-substitutedphenylamino)-1,3,5-triazin-2-ylamino)phenyl)-3-(4-substitutedphenyl)prop-2-en-1-one (2.24) by using 1-(4-(4,6-bis(substitutedphenylamino)-1,3,5-triazin ylamino)phenyl)ethanone (2.23) with different aldehyde under ultrasonic irradiation and subsequently 4-(3-(4,6-bis(4-substituted)-1,3,5-triazin-2-ylamino)phenyl)-4,5-dihydro-1-phenyl-1H-pyrazol-5-yl)substituted (2.25) are formed under ultrasonic irradiation in the presence of phenyl hydrazine and acetic acid. Standard spectrum data were used to describe the pyrazolines, which were produced in high to excellent yields (81-89%). The procedure is straightforward, and the findings show that, unlike traditional heating, ultrasonic irradiation resulted in better yields, faster reaction times (30-40 min.), and milder conditions. [ABSTRACT FROM AUTHOR]