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Selective PI3Kδ inhibitor TYM-3-98 suppresses AKT/mTOR/SREBP1-mediated lipogenesis and promotes ferroptosis in KRAS-mutant colorectal cancer.

Authors :
Zheng, Ya-nan
Lou, Si-yue
Lu, Jun
Zheng, Fan-li
Tang, Yong-mei
Zhang, En-jun
Cui, Sun-liang
Zhao, Hua-jun
Source :
Cell Death & Disease; Jul2024, Vol. 15 Issue 7, p1-10, 10p
Publication Year :
2024

Details

Language :
English
ISSN :
20414889
Volume :
15
Issue :
7
Database :
Complementary Index
Journal :
Cell Death & Disease
Publication Type :
Academic Journal
Accession number :
179067450
Full Text :
https://doi.org/10.1038/s41419-024-06848-7