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Multifpocal ERG in ethambutol associated visual loss.
- Source :
- British Journal of Ophthalmology; Aug2005, Vol. 89 Issue 8, p976-982, 7p, 1 Diagram
- Publication Year :
- 2005
-
Abstract
- Aim: To determine the anatomical site and extent of electrophysiological dysfunction in patients with ethambutol associated visual loss. Methods: A comparative case series. Four patients with ethambutol associated visual loss underwent multifocal electroretinography (mERG). Two patients had advanced visual loss while two had early signs of toxicity. The N1-P1, N1, P1 amplitudes, N1, and P1 latencies were compared to 10 age and sex matched controls. Results: mERG latencies were detected in the ethambutol treated patients. The N1 amplitude was significantly lower in the ethambutol treated patients than in the control group. Conclusion: Ethambutol is possibly toxic the retina, and not only the optic nerve. The multifocal ERG may be of value to diagnose and monitor patients taking ethambutol. [ABSTRACT FROM AUTHOR]
- Subjects :
- VISION disorders
PATIENTS
EYE examination
EYE diseases
RETINA
VISUAL pathways
Subjects
Details
- Language :
- English
- ISSN :
- 00071161
- Volume :
- 89
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- British Journal of Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 17904889
- Full Text :
- https://doi.org/10.1136/bjo.2004.065656