Researcher from PSL Research University Discusses Findings in Rhabdoid Tumors (Post-zygotic mosaicism of SMARCB1 variants in patients with rhabdoid tumors: a not so rare condition exposing to successive tumors).

A recent study conducted by researchers from PSL Research University in Paris, France, has shed light on the prevalence of SMARCB1 mosaicism in rhabdoid tumors (RT). RT is a rare and aggressive form of tumor that primarily affects young children. The study found that a significant number of patients with RT exhibited germline alterations in the SMARCB1 gene, with some cases showing mosaicism in blood samples. The researchers emphasized the need for improved genetic counseling and oncological monitoring due to the potential clinical impact of SMARCB1 mosaicism. [Extracted from the article]