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Effects of preeclampsia on perinatal outcomes in women with gestational diabetes mellitus: A retrospective cohort study.

Authors :
Tian, Ruixue
Xu, Jingqi
He, Jing
Chen, Zhen
Liu, Yanqun
Chen, Xiaoli
Zou, Zhijie
Source :
International Journal of Diabetes in Developing Countries; 2024 Suppl 1, Vol. 44, p53-60, 8p
Publication Year :
2024

Abstract

Background: To date, studies on the effects of preeclampsia on perinatal outcomes in women with gestational diabetes mellitus (GDM) are comparatively few, and the results are inconsistent. Objective: This study aimed to explore the effects of preeclampsia on perinatal outcomes in women with GDM. Methods: This retrospective cohort study collected data of women with GDM whose babies were delivered in a Chinese hospital between July 2017 and June 2020. We divided eligible pregnant women with GDM into two groups based on whether they were diagnosed with preeclampsia: GDM with preeclampsia group and GDM without preeclampsia group. Logistic regression analysis was performed to evaluate the risks for perinatal outcomes which were used as the dependent variables. Results: We identified 7533 eligible women with GDM (245 in GDM with preeclampsia group and 7288 in GDM without preeclampsia group). After adjusting for covariates, preeclampsia was significantly associated with higher risks of fetal malformations (OR: 1.67, 95% CI: 1.08–2.57), fetal growth restriction (OR: 5.36, 95% CI: 2.91–9.88), cesarean section (OR: 2.48, 95% CI: 1.83–3.37), emergency cesarean section (OR: 2.32, 95% CI: 1.77–3.05), preterm birth (OR: 1.89, 95% CI: 1.27–2.81), low birth weight (LBW) (OR: 3.30, 95% CI: 2.16–5.05), small for gestational age (SGA) (OR: 3.05, 95% CI: 2.01–4.63) and neonatal hypoglycemia (OR: 1.77, 95% CI: 1.10–2.85). Conclusion: Women with GDM complicated with preeclampsia were at higher risks of fetal malformations, fetal growth restriction, cesarean section, emergency cesarean section, preterm birth, LBW, SGA and neonatal hypoglycemia. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09733930
Volume :
44
Database :
Complementary Index
Journal :
International Journal of Diabetes in Developing Countries
Publication Type :
Academic Journal
Accession number :
178968807
Full Text :
https://doi.org/10.1007/s13410-023-01236-x