New clues point towards how exercise reduces symptoms of depression.

A new review article published in Translational Psychiatry by researchers from University College London explores the processes in the brain and body through which physical exercise reduces symptoms of depression. The researchers propose a novel hypothesis that suggests the antidepressant effects of exercise may hinge on motivation, which is important for alleviating symptoms of depression such as anhedonia, low energy, and "brain fog." The team suggests that exercise reduces inflammation, boosts dopamine function, and enhances motivation, which could explain its antidepressant effect. The researchers hope that this understanding will inform the development of new treatment strategies for depression, such as personalized exercise programs. [Extracted from the article]