First person – Ke Shan and Trieu Le.

The article features an interview with Ke Shan and Trieu Le, co-first authors of a paper titled "TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling" published in the Journal of Cell Science. The study focuses on the protein TMEM16F and its role in disrupting the arrangement of components in the cell membrane, affecting processes such as blood clotting, fighting infections, and placenta formation. The researchers discovered that TMEM16F also plays a crucial role in forming new blood vessels by affecting proteins and signals that control connections between endothelial cells. They overcame challenges by seeking advice from other labs and integrating various perspectives. The researchers chose the Journal of Cell Science for their paper due to its previous publication on a similar topic and positive experiences from collaborators. They also discuss their mentors and motivations for pursuing a career in science. Ke Shan plans to transition to an R&D role in the biotechnology industry, while Trieu Le is looking for new opportunities in the biotech and pharmaceutical industry. [Extracted from the article]