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Research progress of brain organoids in the field of diabetes.

Authors :
Su, Ying
Liu, Aimei
Chen, Hongguang
Chen, Qingjie
Zhao, Bo
Gao, Runze
Zhang, Kangwei
Peng, Tie
Zhang, Zhenwang
Ouyang, Changhan
Zhu, Dan
Source :
Molecular Brain; 8/6/2024, Vol. 17 Issue 1, p1-14, 14p
Publication Year :
2024

Abstract

Human embryonic stem cells and human induced pluripotent stem cells may be used to create 3D tissues called brain organoids. They duplicate the physiological and pathological characteristics of human brain tissue more faithfully in terms of both structure and function, and they more precisely resemble the morphology and cellular structure of the human embryonic brain. This makes them valuable models for both drug screening and in vitro studies on the development of the human brain and associated disorders. The technical breakthroughs enabled by brain organoids have a significant impact on the research of different brain regions, brain development and sickness, the connections between the brain and other tissues and organs, and brain evolution. This article discusses the development of brain organoids, their use in diabetes research, and their progress. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17566606
Volume :
17
Issue :
1
Database :
Complementary Index
Journal :
Molecular Brain
Publication Type :
Academic Journal
Accession number :
178855672
Full Text :
https://doi.org/10.1186/s13041-024-01123-4