The use of genetic algorithm and particle swarm optimization on tiered feature selection method in machine learning-based coronary heart disease diagnosis system.

Coronary heart disease (CHD) is a leading global cause of death. Early detection is the right step to reduce mortality rates and treatment costs. Early detection can be developed using machine learning by utilizing patient medical record datasets. Unfortunately, this dataset has excessive features which can reduce machine learning performance. For this reason, it is necessary to reduce the number of redundant features and irrelevant data to improve machine learning performance. Therefore, this research proposes a tiered of feature selection model with genetic algorithm (GA) and particle swarm optimization (PSO) to improve the performance of the diagnosis model. The feature selection model is evaluated using parameters derived from the confusion matrix and using the CatBoost machine learning algorithm. Model testing uses z-Alizadeh Sani, Cleveland, Statlog, and Hungarian datasets. The best results for this model were obtained on the z-Alizadeh Sani dataset with 6 selected features from 54 features and the resulting performance for accuracy parameters was 99.32%, specificity 98.57%, sensitivity 100.00%, area under the curve (AUC) 99.28%, and F1-Score 99.37%. The proposed feature selection model is able to provide machine learning performance in the very good category. The diagnostic model proposed is of excellent standard. [ABSTRACT FROM AUTHOR]