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Association of the severity and pattern of pituitary adenoma-related headache with the size and type of adenoma.
- Source :
- Journal of Preventive Epidemiology; Jun2024, Vol. 9 Issue 2, p1-5, 5p
- Publication Year :
- 2024
-
Abstract
- Introduction: Headache is one of the essential symptoms of pituitary adenoma associated with the tumor and the patient’s characteristics. The pattern of adenoma-related headaches varies widely and can significantly impact the patient’s quality of life. Objectives: We aimed to investigate the severity and pattern of headaches in patients with pituitary adenoma in Iran. Patients and Methods: In this cross-sectional study, we investigated 109 patients with an initial complement of headaches. The diagnosis of pituitary adenoma was confirmed. Patients’ demographic characteristics [e.g., gender, body mass index (BMI), and age] and tumor characteristics (e.g., subtype of tumor and size of tumor) were collected by interview, clinical examination, and imaging. We measured the severity of the headache using Headache Impact Test-6 (HIT-6) questionnaire version 1.1. Results: In our study, the most common subtype of pituitary adenoma was prolactinoma, followed by nonfunctional growth hormone (GH)-releasing and adrenocorticotropic hormone (ACTH)-releasing adenomas. Functional adenoma was significantly more common in women; however, the incidence of non-functional adenoma was more in men (61%), indicating the correlation between gender and subtype of adenoma (P = 0.008). Most tumors were functional microadenomas (69%), while macroadenomas were primarily non-functional (50%). The HIT-6 scores demonstrated that functional microadenomas had higher HIT-6 scores and patients with prolactinoma experienced more severe headaches than other subtypes (P = 0.003). Conclusion: Our study revealed significant effects of the type of adenoma on the severity of headaches, as patients with functional microadenomas had more muscular headaches. Additionally, the hormonereleasing function of tumors plays a vital part in the advent and severity of adenoma-related headaches. [ABSTRACT FROM AUTHOR]
- Subjects :
- RISK assessment
CROSS-sectional method
PAIN measurement
BODY mass index
PSYCHOLOGICAL distress
HEADACHE
SEX distribution
INTERVIEWING
QUESTIONNAIRES
PROLACTINOMA
SEVERITY of illness index
AGE distribution
MAGNETIC resonance imaging
DESCRIPTIVE statistics
CHI-squared test
GROWTH hormone-secreting pituitary adenoma
ADRENOCORTICOTROPIC hormone
ONE-way analysis of variance
ANALYSIS of variance
PITUITARY tumors
CUSHING'S syndrome
SOMATOMEDIN
DATA analysis software
COMPARATIVE studies
PSYCHOSOCIAL functioning
COGNITION
DISEASE risk factors
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 24763934
- Volume :
- 9
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Journal of Preventive Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 178744120
- Full Text :
- https://doi.org/10.34172/jpe.2023.35213