Mathematical Modeling of the Drug Particles Deposition in the Human Respiratory System—Part 1: Development of Virtual Models of the Upper and Lower Respiratory Tract.

In order to carry out mathematical modeling of the drug particles or drop movement in the human respiratory system, an approach to reverse prototyping of the studied areas based on the medical data (computed tomography) results is presented. To adapt the computational grid, a mathematical model of airflow in channels of complex geometry (respiratory system) has been developed. Based on the data obtained, the results of computational experiments for a single-phase system are presented. [ABSTRACT FROM AUTHOR]