Back to Search
Start Over
Nutritional Status in Pediatric Psoriasis: A Case–Control Study in a Tertiary Care Referral Centre.
- Source :
- Children; Jul2024, Vol. 11 Issue 7, p885, 14p
- Publication Year :
- 2024
-
Abstract
- Background: Psoriasis and obesity are chronic, inflammatory diseases, sharing certain pathophysiological factors. Psoriasis, increasingly viewed as a systemic inflammatory condition, may have various symptoms beyond the skin manifestations. Methods: This research aimed to explore the connection between body mass index (BMI) and pediatric psoriasis, through a case–control study on 100 psoriasis cases and 100 controls who were matched in terms of age and sex. The percentiles of the BMI by age and sex determined the nutritional status of each patient and control. The severity of psoriasis was evaluated based on the psoriasis area and severity index (PASI), nail involvement based on the nail psoriasis severity index (NAPSI), and quality of life impairment with the dermatology life quality index (DLQI). Results: While no statistically significant relationship was identified between increased BMI and PASI (p = 0.074), the risk of being overweight and obesity was significantly higher in the psoriasis group (OR 6.93, p = 0.003; OR 12.6, p < 0.001, respectively). The BMI increased with the PASI for psoriasis vulgaris but not for psoriasis inverse. No connections were found between disease duration and BMI (p = 0.56) or between BMI and PASI based on sex (p = 0.26). The NAPSI increased significantly with increased BMI (p = 0.000015). Conclusions: This study highlights the association between elevated BMI, psoriasis diagnosis, and severity of psoriatic onychopathy in pediatric patients, advocating for further large-scale studies to confirm these explorations and increasing awareness for better screening and management of such cases for overweight/obese patients. [ABSTRACT FROM AUTHOR]
- Subjects :
- OBESITY risk factors
RISK assessment
PSORIASIS
BODY mass index
DISEASE duration
T-test (Statistics)
SEX distribution
CUTANEOUS manifestations of general diseases
LOGISTIC regression analysis
TERTIARY care
AGE distribution
SEVERITY of illness index
RETROSPECTIVE studies
DESCRIPTIVE statistics
PEDIATRICS
CHRONIC diseases
ODDS ratio
NUTRITIONAL status
QUALITY of life
CASE-control method
MEDICAL records
ACQUISITION of data
INFLAMMATION
CONFIDENCE intervals
MEDICAL referrals
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 178695169
- Full Text :
- https://doi.org/10.3390/children11070885