Findings from Morgan State University in Pancreatic Cancer Reported (Encapsulation of Gemcitabine on Porphyrin Aluminum Metal-Organic Framework by Mechano-Chemistry, Delayed Drug Release and Cytotoxicity to Pancreatic Cancer PANC-1 Cells).

A recent study conducted by researchers at Morgan State University in Baltimore, Maryland, explored the encapsulation of the anticancer drug gemcitabine on a metal-organic framework called porphyrin aluminum. The researchers used a novel technique called mechano-chemistry to encapsulate the drug, resulting in delayed drug release. The study also investigated the cytotoxicity of the encapsulated drug on pancreatic cancer cells. The findings suggest that aluminum metal-organic frameworks could be promising materials for controlled drug release and potential use in drug-eluting implants. [Extracted from the article]