ارزیابی ترکیبات فنولی در اندام هوایی و ریشه کاسنی (.L intybus Cichorium) مناطق مختلف کشور با استفاده از کروماتوگرافی مایع با کارآیی بالا (HPLC).

Chicory is one of the most useful plants in traditional medicine and has various therapeutic properties and chemical compounds. Due to the variety of climatic conditions of Iran, the chemical composition and biological stress of chicory grown in different regions of Iran may be different from chicory grown in other countries. Therefore, this research was conducted to investigate phytochemistry including the identification and measurement of some phenolic compounds in the hydroalcoholic extracts of the Cichorium intybus L. (collected from 6 localities) in order to compare with chicory grown in other parts of the world. Based on the studied articles and existing standards, 9 compounds including chicoric acid, chlorogenic acid, rosmarinic acid, caffeic acid, salicylic acid, gallic acid, catechin, quercetin, and rutin were selected and examined in the extract of the aerial part and roots of the plant by HPLC. Among the studied compounds, chicoric acid (0.55 to 6.04 mg per gram of dry plant), chlorogenic acid (0.50 to 5.37 mg per gram of dry plant), and rutin (0.56 to 2.25 mg per gram of dry plant) were found in the extracts of aerial parts and chicoric acid (0.03% to 0.29 mg per gram of dry plant) and chlorogenic acid (0.84% to 2.88 mg per gram of dry plant) were found in the extracts of roots of all samples. Among the studied populations, the highest amounts of major compounds (chicoric acid and chlorogenic acid) were observed in the aerial parts of the sample collected from the National Botanical Garden of Iran with 6.04 mg of chicoric acid and 5.37 mg chlorogenic acid. The results show that although the amount of main compounds of the cultivated sample is different from of that of wild samples, but the nature of the main compounds and the pattern of the HPLC spectrum of all the samples are close to each other and similar to the chicory grown outside of Iran. [ABSTRACT FROM AUTHOR]