Patent Issued for Methods of treating gastrointestinal stromal tumors (USPTO 12023325).

A patent has been issued to Deciphera Pharmaceuticals LLC for methods of treating gastrointestinal stromal tumors (GIST). GISTs are rare tumors that occur in the gastrointestinal tract, with the majority of cases caused by mutations in the KIT or PDGFRA genes. The patent describes a method of treating advanced GIST by administering ripretinib, a tyrosine kinase inhibitor, to patients who have previously been treated with imatinib. The treatment aims to provide more than 3 months of progression-free survival in patients. The patent also includes various dosage regimens for ripretinib administration. [Extracted from the article]