Researchers Submit Patent Application, "Method For Training Binding Affinity Detection Model And Binding Affinity Detection Method", for Approval (USPTO 20240220685).

A patent application has been submitted by Tencent Technology (Shenzhen) Company Limited for a method to train a binding affinity detection model and a binding affinity detection method. The method involves obtaining protein structure data, small molecule structure data, and a sample labeling result indicating the binding affinity between the protein and the small drug molecule. A neural network model is then used to determine the structure data of target complex conformations and a sample prediction result. The neural network model is trained using the sample prediction result and the sample labeling result to obtain a binding affinity detection model. This method aims to improve the accuracy of the binding affinity detection model, which can be used to assess the druggability potential of small drug molecules. [Extracted from the article]