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68Ga-DOATATOC Brain PET/CT Imaging in a case of Dural Metastasis from Synovial Sarcoma.
- Source :
- Nuclear Medicine & Molecular Imaging; Aug2024, Vol. 58 Issue 5, p310-316, 7p
- Publication Year :
- 2024
-
Abstract
- We present the case of a 70-year-old male patient who underwent a gallium-68 (<superscript>68</superscript>Ga)-DOTATOC brain positron emission tomography (PET)/computed tomography (CT) for the assessment of a tumorous lesion on the dura. The patient had previously undergone below-knee amputation due to a mass of synovial sarcoma on the left foot and completed adjuvant chemotherapy approximately 3 months ago. Subsequently, a well-demarcated papillary solid mass located on the dura was surgically excised. Pathological examination confirmed that the dural metastasis originated from synovial sarcoma and post-operative magnetic resonance imaging (MRI) revealed no residual tumor. We conducted a <superscript>68</superscript>Ga-DOTATOC brain PET/CT suspecting a meningioma given the presence of a dural mass. The result showed lower uptake (maximum standardized uptake [SUV<subscript>max</subscript> 4.9]) than the pituitary gland (SUV<subscript>max</subscript> 9.3). Thus, we successfully conducted a differential diagnosis of metastasis from the preexisting malignancy rather than the meningioma. <superscript>68</superscript>Ga-DOTATOC PET/CT is a valuable tool for the differential diagnosis of meningioma. However, metastasis should also be considered, especially in patients with a history of malignancy and lesions showing mild <superscript>68</superscript>Ga-DOTATOC uptake. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18693474
- Volume :
- 58
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Nuclear Medicine & Molecular Imaging
- Publication Type :
- Academic Journal
- Accession number :
- 178504367
- Full Text :
- https://doi.org/10.1007/s13139-024-00854-5