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Migraine in multiple sclerosis patients: potential links and treatment approach Panagiotis Gklinos and Dimos-Dimitrios Mitsikostas.

Migraine in multiple sclerosis patients: potential links and treatment approach Panagiotis Gklinos and Dimos-Dimitrios Mitsikostas.

Authors :
Gklinos, Panagiotis
Mitsikostas, Dimos-Dimitrios
Source :
Expert Opinion on Pharmacotherapy; 2023, Vol. 24 Issue 17, p1845-1851, 7p
Publication Year :
2023

Abstract

Introduction: Migraine has been reported to be twice as prevalent in patients with multiple sclerosis (MS) compared to the non-MS population. However, prospective, controlled studies that could lead to robust conclusions are still lacking. Areas covered: Treatment of migraine in patients with MS can be challenging. Comorbidities need to be assessed and managed early, and preventive treatment should be initiated when indicated. Caution is warranted regarding the selection of the preventive medication since certain agents can magnify MS symptoms and particularly cognitive symptoms. This paper aims to discuss the association of MS and migraine, shed light on distinguishing points and red flags, as well as offer practical advice on the selection of treatment according to patients' characteristics. Expert opinion: A holistic approach including pharmacological and non-pharmacological modifications is required to treat migraine in patients with MS effectively. Anti-CGRP monoclonal antibodies are a promising option due to limited drug-to-drug interactions; however, larger prospective studies are required to draw robust conclusions on the concomitant use of anti-CGRPs with MS disease modifying treatments. Early migraine preventive treatment might be needed to reduce the burden of disease in patients with MS. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14656566
Volume :
24
Issue :
17
Database :
Complementary Index
Journal :
Expert Opinion on Pharmacotherapy
Publication Type :
Academic Journal
Accession number :
178496810
Full Text :
https://doi.org/10.1080/14656566.2023.2262384