Study Findings on T-Cell Lymphoma Discussed by a Researcher at University of Pennsylvania (The CNS relapse in T-cell lymphoma index predicts CNS relapse in patients with T- and NK-cell lymphomas).

A recent study conducted by researchers at the University of Pennsylvania has focused on the risk factors for central nervous system (CNS) relapse in patients with mature T-cell and natural killer cell neoplasms (MTNKNs). The researchers developed the CNS relapse In T-cell lymphoma Index (CITI) to predict patients at the highest risk of CNS relapse. The study found that CNS relapse was most frequently observed in patients with peripheral T-cell lymphoma, not otherwise specified, and the median time to CNS relapse and median overall survival after CNS relapse were 8.0 and 4.7 months, respectively. The CITI score was validated as a model to predict patients with MTNKN at the highest risk of developing CNS relapse. [Extracted from the article]