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Researcher at NovAliX Publishes New Study Findings on Small Molecule Inhibitors (Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance).
- Source :
- Drug Week; 7/12/2024, p2478-2478, 1p
- Publication Year :
- 2024
-
Abstract
- A recent study conducted by researchers at NovAliX in Strasbourg, France, has explored the affinity and kinetics of small molecule inhibitors of galectin-1 using surface plasmon resonance (SPR). Galectin-1 is a protein that binds to cell surface glycoproteins and has been implicated in various cancers. The study found that SPR is a viable alternative to fluorescence polarization (FP) assays for early drug discovery screening and determining affinity estimates. This research provides valuable insights into the development of small molecule galectin-1 inhibitors. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Complementary Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 178241633