Researchers from Ohio State University Publish Findings in Personalized Medicine (Sex-related DNA methylation is associated with inflammation and gene expression in the lungs of healthy individuals).

A recent study conducted by researchers from Ohio State University has found that lung cancer exhibits sex-related molecular characteristics and epidemiological trends, suggesting the need for sex-specific approaches to understanding its causes and treatment. The study focused on DNA methylation alterations, which play a critical role in lung cancer development and can serve as valuable biomarkers for personalized medicine strategies. The researchers identified sex-related differentially methylated CpG sites (DM-CpGs) in the lungs of healthy individuals and correlated them with gene expression and immune responses. These findings highlight the potential role of sex-related CpGs in influencing sex disparities in lung cancer risk and outcomes, emphasizing the need for further investigation in personalized lung cancer management strategies. [Extracted from the article]