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Radiology of fibrosis. Part I: Thoracic organs.

Authors :
Tarchi, Sofia Maria
Salvatore, Mary
Lichtenstein, Philip
Sekar, Thillai
Capaccione, Kathleen
Luk, Lyndon
Shaish, Hiram
Makkar, Jasnit
Desperito, Elise
Leb, Jay
Navot, Benjamin
Goldstein, Jonathan
Laifer, Sherelle
Beylergil, Volkan
Ma, Hong
Jambawalikar, Sachin
Aberle, Dwight
D'Souza, Belinda
Bentley-Hibbert, Stuart
Marin, Monica Pernia
Source :
Journal of Translational Medicine; 7/2/2024, Vol. 22 Issue 1, p1-18, 18p
Publication Year :
2024

Abstract

Sustained injury from factors such as hypoxia, infection, or physical damage may provoke improper tissue repair and the anomalous deposition of connective tissue that causes fibrosis. This phenomenon may take place in any organ, ultimately leading to their dysfunction and eventual failure. Tissue fibrosis has also been found to be central in both the process of carcinogenesis and cancer progression. Thus, its prompt diagnosis and regular monitoring is necessary for implementing effective disease-modifying interventions aiming to reduce mortality and improve overall quality of life. While significant research has been conducted on these subjects, a comprehensive understanding of how their relationship manifests through modern imaging techniques remains to be established. This work intends to provide a comprehensive overview of imaging technologies relevant to the detection of fibrosis affecting thoracic organs as well as to explore potential future advancements in this field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14795876
Volume :
22
Issue :
1
Database :
Complementary Index
Journal :
Journal of Translational Medicine
Publication Type :
Academic Journal
Accession number :
178230342
Full Text :
https://doi.org/10.1186/s12967-024-05244-1