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Evaluation of the Protective and Healing Effects of Heracleum lasiopetalum Boiss on a Modified Acetic Acid-Induced Ulcerative Colitis Model in Rats.

Authors :
Malekshahi, Hossein
Bahrami, Gholamreza
Babaei, Atefeh
Miraghaee, Shahram
Jalilian, Nastaran
Madani, Seyed Hamid
Farzaei, Mohammad Hosein
Source :
Jundishapur Journal of Natural Pharmaceutical Products; May2024, Vol. 19 Issue 3, p1-12, 12p
Publication Year :
2024

Abstract

The article focuses on evaluating the therapeutic effects of Heracleum lasiopetalum Boiss in a rat model of acetic acid-induced ulcerative colitis (UC). It reports that Heracleum lasiopetalum extract reduces colon hyperemia, mucosal ulceration, inflammation, and fibrosis in a dose-dependent manner, suggesting its potential as an adjunct therapy for UC, warranting further investigation.

Details

Language :
English
ISSN :
17357780
Volume :
19
Issue :
3
Database :
Complementary Index
Journal :
Jundishapur Journal of Natural Pharmaceutical Products
Publication Type :
Academic Journal
Accession number :
178200369
Full Text :
https://doi.org/10.5812/jjnpp-143801