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Malnutrition-Related Liver Steatosis, CONUT Score and Poor Clinical Outcomes in an Internal Medicine Department.

Authors :
Miano, Nicoletta
Todaro, Giorgia
Di Marco, Maurizio
Scilletta, Sabrina
Bosco, Giosiana
Di Giacomo Barbagallo, Francesco
Scicali, Roberto
Piro, Salvatore
Purrello, Francesco
Di Pino, Antonino
Source :
Nutrients; Jun2024, Vol. 16 Issue 12, p1925, 9p
Publication Year :
2024

Abstract

Fatty liver disease has been identified as a marker of malnutrition in different clinical settings. Recently, the COntrolling NUTritional status score (CONUT score) emerged as a promising tool for malnutrition assessment. Our aim was to evaluate short-term outcomes among patients with malnutrition-related liver steatosis in an Internal Medicine department. Furthermore, we evaluated the association of the CONUT score with malnutrition-related liver steatosis. Data from 247 patients hospitalized in an Internal Medicine department were retrospectively collected. The study population was stratified into three groups based on hepatic radiodensity assessed with computed tomography: mild steatosis (≥56.1 HU), moderate steatosis (between 49.7 and 56 HU), and severe steatosis (≤49.6 HU). We then calculated the CONUT score. Severe steatosis patients had higher in-hospital mortality (18.2 vs. 15.5%) and longer in-hospital stays compared with the mild steatosis group (length of in-hospital stay longer than 12 days: 45% vs. 40%). Logistic regression analysis showed that severe steatosis was not significantly associated with in-hospital all-cause death, while a high CONUT score was an independent risk factor for sepsis. We found an independent relationship between malnutrition-associated liver steatosis and the CONUT score. These results identified the CONUT score as a tool for nutritional assessment of hospitalized patients. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20726643
Volume :
16
Issue :
12
Database :
Complementary Index
Journal :
Nutrients
Publication Type :
Academic Journal
Accession number :
178191529
Full Text :
https://doi.org/10.3390/nu16121925