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Study of Correlation between Fetal Bowel Dilation and Congenital Gastrointestinal Malformation.
- Source :
- Children; Jun2024, Vol. 11 Issue 6, p670, 11p
- Publication Year :
- 2024
-
Abstract
- Background: Ultrasound serves as a valuable tool for the early detection of fetal bowel dilatation, yet the correlation between fetal bowel dilatation and gastrointestinal malformations remains to be further investigated. This study aims to explore the relationship by conducting a follow-up and analysis of fetuses with bowel dilation. Methods: A retrospective analysis was conducted on 113 fetuses with bowel dilatation at our center from July 2014 to December 2019. The location and degree of bowel dilatation were analyzed. ROC curves were constructed based on the diameter of the bowel and its ratio to fetal gestational age. Results: In total, 40 of 41 cases (97.6%) with upper gastrointestinal dilatation (double-bubble sign) and 46 of 72 cases (63.9%) with lower gastrointestinal dilatation were diagnosed with gastrointestinal malformations postnatally. The AUC of the dilatation diameter was 0.854 with a cutoff value of 18.05 mm in patients with lower gastrointestinal dilatation. The ratio of the diameter to gestational age (D/GA) showed a higher AUC of 0.906 with a cutoff value of 0.4931. Conclusions: The presence of the double-bubble sign in fetuses indicates a close association with duodenal obstruction. The risk of gastrointestinal malformations increases when the bowel diameter exceeds 18.05 mm, particularly when the D/GA surpasses 0.4931. [ABSTRACT FROM AUTHOR]
- Subjects :
- INTESTINAL disease diagnosis
DIAGNOSIS of fetal diseases
GASTROINTESTINAL system abnormalities
RISK assessment
STATISTICAL correlation
RESEARCH funding
RECEIVER operating characteristic curves
T-test (Statistics)
SCIENTIFIC observation
QUESTIONNAIRES
DIGESTIVE organ abnormalities
PRENATAL diagnosis
TERTIARY care
RETROSPECTIVE studies
MAGNETIC resonance imaging
DESCRIPTIVE statistics
CHI-squared test
MANN Whitney U Test
FETAL ultrasonic imaging
INTESTINAL diseases
PEDIATRICS
POLYHYDRAMNIOS
MEGACOLON
RESEARCH
GESTATIONAL age
ANALYSIS of variance
FETAL diseases
DUODENAL obstructions
HYDRONEPHROSIS
COMPARATIVE studies
DATA analysis software
CONFIDENCE intervals
NONPARAMETRIC statistics
BOWEL obstructions
DISEASE risk factors
FETUS
Subjects
Details
- Language :
- English
- ISSN :
- 22279067
- Volume :
- 11
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Children
- Publication Type :
- Academic Journal
- Accession number :
- 178159646
- Full Text :
- https://doi.org/10.3390/children11060670