The Influence of the Combinative Continuous and Pulse Application of Lacto-Immuno-Vital Synbioticum on the Mucus Production Dynamics in Poultry Small Intestine.

A great interest is placed on the influence of probiotic, prebiotic and synbiotic preparations on animals in accordance with the principle of One health. The small intestine mucosa represents a complex ecosystem ensuring the homeostasis of the animal organism. The effect of Lacto-Immuno-Vital synbiotic preparation on the quantity of mucin produced in the broiler chicken small intestine was studied. The chickens (7 days old Hybrid ROSS 308) were divided into 3 equal size (n = 16) groups, housed in separate halls: control group (CG), and two experimental groups that received syn-biotic preparation Lacto-Immuno-Vital, – one with continuous synbiotic administration (EGC), and another with pulsed synbiotic administration (EGP). The preparation was administered to EGC group from the experimental day 1 to day 7 continuously every day (500 g per 1000 l of drinking water.day⁻¹), and to EGP group from experimental day 8 to day 22 in a pulsed manner (every third day) at a dose of 300 g per 1000 l of drinking water. The experiment lasted 22 days. A significant effect on mucus production quantity was found in the duodenum (P < 0.001), in EG after both types of synbiotic supplementation compared to CG. The comparison of continuous and pulsed supplementation was as follows: a significant effect (P < 0.001) was observed after continuous supplementation of the synbiotic preparation, compared to pulsed supplementation in EG. [ABSTRACT FROM AUTHOR]