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Development of a prediction model for suicidal ideation in patients with advanced cancer: A multicenter, real‐world, pan‐cancer study in China.

Authors :
He, Yi
Pang, Ying
Yang, Wenlei
Su, Zhongge
Wang, Yu
Lu, Yongkui
Jiang, Yu
Zhou, Yuhe
Han, Xinkun
Song, Lihua
Wang, Liping
Li, Zimeng
Lv, Xiaojun
Wang, Yan
Yao, Juntao
Liu, Xiaohong
Zhou, Xiaoyi
He, Shuangzhi
Zhang, Yening
Song, Lili
Source :
Cancer Medicine; Jun2024, Vol. 13 Issue 12, p1-11, 11p
Publication Year :
2024

Abstract

Background: Patients diagnosed with advanced stage cancer face an elevated risk of suicide. We aimed to develop a suicidal ideation (SI) risk prediction model in patients with advanced cancer for early warning of their SI and facilitate suicide prevention in this population. Patients and Methods: We consecutively enrolled patients with multiple types of advanced cancers from 10 cancer institutes in China from August 2019 to December 2020. Demographic characteristics, clinicopathological data, and clinical treatment history were extracted from medical records. Symptom burden, psychological status, and SI were assessed using the MD Anderson Symptom Inventory (MDASI), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire‐9 (PHQ‐9), respectively. A multivariable logistic regression model was employed to establish the model structure. Results: In total, 2814 participants were included in the final analysis. Nine predictors including age, sex, number of household members, history of previous chemotherapy, history of previous surgery, MDASI score, HADS‐A score, HADS‐D score, and life satisfaction were retained in the final SI prediction model. The model achieved an area under the curve (AUC) of 0.85 (95% confidential interval: 0.82–0.87), with AUCs ranging from 0.75 to 0.95 across 10 hospitals and higher than 0.83 for all cancer types. Conclusion: This study built an easy‐to‐use, good‐performance predictive model for SI. Implementation of this model could facilitate the incorporation of psychosocial support for suicide prevention into the standard care of patients with advanced cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20457634
Volume :
13
Issue :
12
Database :
Complementary Index
Journal :
Cancer Medicine
Publication Type :
Academic Journal
Accession number :
178131402
Full Text :
https://doi.org/10.1002/cam4.7439