MODELING OF FERRIC NANOPARTICLES Fe3+ INTERACTIONS WITH THIN FILMS OF ORGANIC SUBSTANCES.

The results of solving the problem of modeling the interaction of iron Fe³⁺ nanoparticles with thin bilayer membranes were represented. The purpose of the work was to create a physical model of the behavior and interaction of Fe3+ iron nanoparticles, which are located near thin films of organic substances. For this, physical model systems with thin films - BPM (bilayer phospholipid membranes) and BLM (bilayer lipid membranes) were considered and analyzed, and iron nanoparticles were introduced into these systems. To fulfill the given task, the data search methods ("data mining") obtained by the gas-liquid chromatography were used, as well as ones obtained in experiments with registration of transmembrane electric currents through artificial two-layer BPM and BLM membranes, and partially ones from the experiments on natural membranes with technique of voltage clamp. Since the applied FeCl3 undergoes hydrolysis, the formed hydroxyl groups interact with BLM membranes, also participating in the sum of interaction effects. Thus, it was concluded about the important role of hydroxyl groups in the mechanism of anionic selectivity of BLM, which is a confirmation of previously obtained research data. A number of effects with participation of ionophores, which increase the ion permeability of artificial BLM membranes, were also considered; they can bind metal ions due to iondipole interaction. The described system with a membrane and iron (III) ions located near it can be used to study a number of phenomena on both artificial and natural membranes, for example, when iron nanoparticles were absorbed by human body from the environment. For all considered cases, known physical and physico-chemical regularities and the corresponding developed mathematical apparatus were verified. Namely, analytical expressions based on electrostatic interactions of electric charges associated with Fe³⁺ ions and localized on membrane surfaces were valid for describing the considered effects. The considered model membranes are on the border between living and non-living nature. At the same time, these systems are simple systems to which the laws of physics and physical chemistry are applicable. And, in some cases, when developing some technical hybrid systems, they can play the role of biosensors. Due to their simplicity, such models can be reproduced quite easily in the conditions of experiments, substances testing with analytical purpose in extreme situations. Therefore, such simple, reliable, tested methods can be used in wartime situations with limited laboratory resources. [ABSTRACT FROM AUTHOR]