Back Cover: A Fluorinated Chaperone Gives X‐ray Crystal Structures of Acyclic Natural Product Derivatives up to 338 Molecular Weight (Angew. Chem. Int. Ed. 27/2024).

A new crystallization chaperone called TFM has been developed, which allows for the formation of X-ray diffraction-based crystal structures of liquid molecules that would otherwise be difficult to obtain. This chaperone acts like a glove that can fit molecules of various sizes, resulting in successful crystallization. The article also introduces a new temperature jump crystallization protocol. The cover graphic of the article displays the chaperone and the crystal lattice of the squalene solvate. [Extracted from the article]