Thought on "Isolation and Phenotypic Characterization of Virulent Bacteriophages Against Multidrug-Resistant Escherichia Coli and Its Phage-Resistant Variant from Sewage Sources" [Letter].

This document is a letter written by Meity Mardiana, Dodi Safari, and Rosantia Sarassari in response to an article by Fikadu et al. The original article discussed the isolation and characterization of phages that infect multidrug-resistant Escherichia coli (MDR-E. coli). The authors of the letter suggest improvements for future studies, such as using the minimum inhibitory concentration (MIC) method to identify MDR-E. coli and including electron microscopy (EM) data to analyze the morphological differences among the phages. They also propose conducting phenotypic analysis on phage-resistant strains to observe any changes in colony appearance. The letter emphasizes the importance of understanding phage resistance mechanisms and developing more effective treatment strategies against bacterial infections. [Extracted from the article]