Back to Search Start Over

Bayesian semi-parametric inference for clustered recurrent events with zero inflation and a terminal event.

Authors :
Tian, Xinyuan
Ciarleglio, Maria
Cai, Jiachen
Greene, Erich J
Esserman, Denise
Li, Fan
Zhao, Yize
Source :
Journal of the Royal Statistical Society: Series C (Applied Statistics); Jun2024, Vol. 73 Issue 3, p598-620, 23p
Publication Year :
2024

Abstract

Recurrent events are common in clinical studies and are often subject to terminal events. In pragmatic trials, participants are often nested in clinics and can be susceptible or structurally unsusceptible to the recurrent events. We develop a Bayesian shared random effects model to accommodate this complex data structure. To achieve robustness, we consider the Dirichlet processes to model the residual of the accelerated failure time model for the survival process as well as the cluster-specific shared frailty distribution, along with an efficient sampling algorithm for posterior inference. Our method is applied to a recent cluster randomized trial on fall injury prevention. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00359254
Volume :
73
Issue :
3
Database :
Complementary Index
Journal :
Journal of the Royal Statistical Society: Series C (Applied Statistics)
Publication Type :
Academic Journal
Accession number :
177947805
Full Text :
https://doi.org/10.1093/jrsssc/qlae003