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Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy.

Authors :
Zafar, Aasma
Khan, Muhammad Jawad
Abu, Junaid
Naeem, Aisha
Source :
Molecular Biology Reports; 1/28/2024, Vol. 51 Issue 1, p1-14, 14p
Publication Year :
2024

Abstract

Despite the availability of technological advances in traditional anti-cancer therapies, there is a need for more precise and targeted cancer treatment strategies. The wide-ranging shortfalls of conventional anticancer therapies such as systematic toxicity, compromised life quality, and limited to severe side effects are major areas of concern of conventional cancer treatment approaches. Owing to the expansion of knowledge and technological advancements in the field of cancer biology, more innovative and safe anti-cancerous approaches such as immune therapy, gene therapy and targeted therapy are rapidly evolving with the aim to address the limitations of conventional therapies. The concept of immunotherapy began with the capability of coley toxins to stimulate toll-like receptors of immune cells to provoke an immune response against cancers. With an in-depth understating of the molecular mechanisms of carcinogenesis and their relationship to disease prognosis, molecular targeted therapy approaches, that inhibit or stimulate specific cancer-promoting or cancer-inhibitory molecules respectively, have offered promising outcomes. In this review, we evaluate the achievement and challenges of these technically advanced therapies with the aim of presenting the overall progress and perspective of each approach. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03014851
Volume :
51
Issue :
1
Database :
Complementary Index
Journal :
Molecular Biology Reports
Publication Type :
Academic Journal
Accession number :
177878382
Full Text :
https://doi.org/10.1007/s11033-023-09096-8