Patent Issued for Compositions and methods for treating non-age-associated hearing impairment in a human subject (USPTO 11993777).

Akouos Inc. has been issued a patent for compositions and methods to treat non-age-associated hearing impairment in humans. The patent provides an overview of the complexity of the ear and the different disorders that can cause hearing loss. It explains the various types of hearing loss, including conductive and sensorineural, and discusses the genetic and environmental factors that can contribute to hearing impairment. The patent focuses on a specific type of hearing loss called non-syndromic sensorineural hearing loss and describes a composition and method for treating it. The invention involves using different nucleic acid vectors to generate a sequence that encodes an active otoferlin protein, which can help treat hearing loss in mammals. The patent also includes various embodiments and claims related to the composition and its components. [Extracted from the article]