Real-time Biomechanical Characterisation of Cytoskeletal Remodelling.

This article discusses the use of quantitative Atomic Force Microscopy (Q-AFM) to study the biomechanical properties of human mesenchymal stem cells (hMSCs) and their cytoskeleton structure. The researchers used cytoskeleton disruptors to observe changes in cell stiffness, which is primarily governed by the cytoskeleton network. The study demonstrates the capability of Q-AFM to perform real-time biomechanical characterization of living cells, providing insights into intracellular structure and cytoskeletal remodeling. It is important to note that this research has not yet undergone peer review. [Extracted from the article]