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Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments.

Authors :
Hovis, Gabrielle
Chandra, Neha
Kejriwal, Nidhi
Hsieh, Kaleb Jia-Yi
Chu, Alison
Yang, Isaac
Wadehra, Madhuri
Source :
International Journal of Molecular Sciences; Jun2024, Vol. 25 Issue 11, p6118, 20p
Publication Year :
2024

Abstract

Glioblastoma is a highly aggressive neoplasm and the most common primary malignant brain tumor. Endothelial tissue plays a critical role in glioblastoma growth and progression, facilitating angiogenesis, cellular communication, and tumorigenesis. In this review, we present an up-to-date and comprehensive summary of the role of endothelial cells in glioblastomas, along with an overview of recent developments in glioblastoma therapies and tumor endothelial marker identification. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16616596
Volume :
25
Issue :
11
Database :
Complementary Index
Journal :
International Journal of Molecular Sciences
Publication Type :
Academic Journal
Accession number :
177850843
Full Text :
https://doi.org/10.3390/ijms25116118