The role of microRNA-200a in the occurrence and development of liver disease.

microRNA (miRNA) is a type of small non-coding RNA that can participate in cell proliferation and apoptosis by regulating gene expression. More and more evidences show that miRNA-200a is involved in the occurrence and development of non-alcoholic fatty liver disease, alcoholic liver disease, drug-induced liver injury, liver fibrosis, and hepatocellular carcinoma. This article summarizes the differences between miRNA-200a by targeting Downstream target genes of serotonin, regulating related signal pathways and playing different roles in the progression of a variety of liver diseases, provide a reference for exploring the mechanism of a variety of liver diseases. [ABSTRACT FROM AUTHOR]