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Prefrontal activity and heart rate variability during cognitive tasks may show different changes in young and older adults with and without mild cognitive impairment.
- Source :
- Frontiers in Aging Neuroscience; 2024, p1-9, 9p
- Publication Year :
- 2024
-
Abstract
- Background: Age-related decline in cognitive function is often linked to changed prefrontal cortex (PFC) activity and heart rate variability (HRV). Mild cognitive impairment (MCI), a transitional stage between normal aging and dementia, might have further degeneration beyond aging. This study aimed to investigate the differences between young and older adults with or without MCI in cognitive functions, task-induced PFC activation and HRV changes. Methods: Thirty-one healthy young adults (YA), 44 older adults (OA), and 28 older adults with MCI (OA-MCI) were enrolled and compared in this crosssectional study. Each participant received a one-time assessment including cognitive and executive functions, as well as the simultaneous recording of PFC activity and HRV during a cognitive task paradigm. Results: We observed age-related decrease in global cognitive functions, executive functions, HRV, and increase in PFC activity. The MCI further deteriorated the global cognitive and executive performances, but not the HRV or the prefrontal activation. Conclusion: Older people showed lower performances in general cognitive function and executive function, compensatory increase of PFC activity, and reduced HRV. Older people with MCI had further deterioration in cognitive performance, but not in PFC activation and HRV. [ABSTRACT FROM AUTHOR]
- Subjects :
- MOTOR ability
CROSS-sectional method
MILD cognitive impairment
COGNITIVE testing
DATA analysis
RESEARCH funding
PREFRONTAL cortex
EXECUTIVE function
KRUSKAL-Wallis Test
AGE distribution
NEAR infrared spectroscopy
DESCRIPTIVE statistics
CHI-squared test
MANN Whitney U Test
HEART beat
ELECTROCARDIOGRAPHY
AGING
ONE-way analysis of variance
STATISTICS
COMPARATIVE studies
DATA analysis software
OLD age
ADULTS
Subjects
Details
- Language :
- English
- ISSN :
- 16634365
- Database :
- Complementary Index
- Journal :
- Frontiers in Aging Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 177809007
- Full Text :
- https://doi.org/10.3389/fnagi.2024.1392304