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A low-calorie meal replacement improves body composition and metabolic parameters in shift workers with overweight and obesity: a randomized, controlled, parallel group trial.
- Source :
- Nutrition & Metabolism; 6/10/2024, Vol. 21 Issue 1, p1-11, 11p
- Publication Year :
- 2024
-
Abstract
- Background: Shift work has been identified as a risk factor for several chronic health conditions including obesity. This study evaluated the impact of a low-calorie meal replacement (MR) as a dinner substitute on body composition and metabolic parameters in shift workers with overweight and obesity. Methods: An 8-week parallel, randomized controlled trial was conducted on overweight and obese shift workers in a large hospital. An intervention group (IG) (n = 25) was provided with a low-calorie MR shake (∼200 kcal) as a replacement for dinner, every day for 8 weeks, while the control group (CG) (n = 25) continued their habitual diet. Anthropometric measurements, body composition, biochemical, and lifestyle data were assessed at the first and last visits. Analyses were done per protocol (PP) and by intention to treat (ITT). Results: Over the study duration, both groups displayed moderate changes in anthropometric measurements and body composition, although these were not statistically significant according to the PP analysis. In the ITT analysis, apart from the hip circumference (HC), all other anthropometric parameters demonstrated significant group and time interactions, suggesting the advantageous effects of the meal replacement over the study period (P < 0.05). HDL and VLDL cholesterol measures showed significant main effects, influenced by both group (P = 0.031) and time (P = 0.050) respectively. The most pronounced dietary shift in the IG was a reduction in carbohydrate consumption and an increase in protein intake. Throughout the study, the meal replacement was well-tolerated, with no adverse events reported. Conclusions: The meal replacement dietary intervention appears to offer beneficial health effects over time. Extended research is crucial to understand the broader implications of meal replacements across diverse populations. Trial registration: Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12622000231741. Registered on 09 February 2022. https://www.anzctr.org.au/ACTRN12622000231741.aspx. [ABSTRACT FROM AUTHOR]
- Subjects :
- BLOOD sugar analysis
LIFESTYLES
HIGH density lipoproteins
WEIGHT loss
HDL cholesterol
GLYCOSYLATED hemoglobin
FOOD consumption
BODY composition
LIPIDS
STATISTICAL sampling
TREATMENT effectiveness
RANDOMIZED controlled trials
HOSPITALS
LDL cholesterol
BIOCHEMISTRY
HIP joint
LOW density lipoproteins
CHOLESTEROL
MEALS
COMPARATIVE studies
ANTHROPOMETRY
DIETARY carbohydrates
DIETARY proteins
REDUCING diets
SHIFT systems
Subjects
Details
- Language :
- English
- ISSN :
- 17437075
- Volume :
- 21
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Nutrition & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 177797358
- Full Text :
- https://doi.org/10.1186/s12986-024-00799-8