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Inhibition of astrocytic glycine transporter-1: friend or foe for ameliorating NMDA receptor hypofunction?

Authors :
Singer, Philipp
Yee, Benjamin K.
Source :
Frontiers in Cellular Neuroscience; 2024, p1-6, 6p
Publication Year :
2024

Abstract

This document is a compilation of scientific articles and studies that explore the role of glycine transporters in schizophrenia and other psychiatric disorders. The articles discuss the mechanisms of glycine release and the potential therapeutic targets for treating schizophrenia. They also examine the effects of glycine augmentation on symptoms and explore the use of glycine transporter inhibitors as potential treatments for cognitive impairment and negative symptoms associated with schizophrenia. [Extracted from the article]

Details

Language :
English
ISSN :
16625102
Database :
Complementary Index
Journal :
Frontiers in Cellular Neuroscience
Publication Type :
Academic Journal
Accession number :
177785721
Full Text :
https://doi.org/10.3389/fncel.2024.1389718