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Health-related quality of life and associated risk factors in patients with Multiple Osteochondromas: a cross-sectional study.
- Source :
- Quality of Life Research; May2024, Vol. 33 Issue 5, p1323-1334, 12p
- Publication Year :
- 2024
-
Abstract
- Purpose: To evaluate the health-related quality of life and associated risk factors for Multiple Osteochondromas patients. Methods: A cross-sectional, observational study was conducted from May to December 2022 during the routine visit to the referral center for rare skeletal disorders. All patients with Multiple Osteochondromas aged ≥ 3 years were included. EuroQol 5-dimension questionnaires, and demographic, clinical, and surgical history data were collected. Descriptive statistics, Fisher's exact test, One-sample t-test, Spearman's correlation, and multiple linear and logistic regression were performed to analyze the data. Results are reported following STROBE guidelines. Results: A total of 128 patients were included in the study, with a mean age of 14 [SD, 10] years. The mean EQ-5D Index Value was 0.863 [SD, 0.200] and the EQ-VAS was 84 [SD, 19] with a positive correlation between two scores [r = 0.541, p < 0.001]. Patients frequently referred problems in pain/discomfort [78.8%], anxiety/depression [50%], and usual activities [38.8%] dimensions. Increasing age was the common risk factor for health-related quality of life [p < 0.000], as well as Index Value and VAS scores were significantly lower in surgical patients [p = 0.001 and p < 0.001, respectively]. Conclusion: Increasing age and surgical procedures were found highly associated with reduced health-related quality of life in Multiple Osteochondromas patients. Our findings provide relevant information to support the establishment of patient-centered healthcare pathways and pave the way for further research into medical and non-medical therapeutic strategies for these patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09629343
- Volume :
- 33
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Quality of Life Research
- Publication Type :
- Academic Journal
- Accession number :
- 177776366
- Full Text :
- https://doi.org/10.1007/s11136-024-03604-4