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Use of new and emerging cancer drugs: what the cardiologist needs to know.

Authors :
Fabiani, Iacopo
Chianca, Michela
Aimo, Alberto
Emdin, Michele
Dent, Susan
Fedele, Antonella
Cipolla, Carlo Maria
Cardinale, Daniela Maria
Source :
European Heart Journal; 6/7/2024, Vol. 45 Issue 22, p1971-1987, 17p
Publication Year :
2024

Abstract

The last decade has witnessed a paradigm shift in cancer therapy, from non-specific cytotoxic chemotherapies to agents targeting specific molecular mechanisms. Nonetheless, cardiovascular toxicity of cancer therapies remains an important concern. This is particularly relevant given the significant improvement in survival of solid and haematological cancers achieved in the last decades. Cardio-oncology is a subspecialty of medicine focusing on the identification and prevention of cancer therapy–related cardiovascular toxicity (CTR-CVT). This review will examine the new definition of CTR-CVT and guiding principles for baseline cardiovascular assessment and risk stratification before cancer therapy, providing take-home messages for non-specialized cardiologists. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0195668X
Volume :
45
Issue :
22
Database :
Complementary Index
Journal :
European Heart Journal
Publication Type :
Academic Journal
Accession number :
177720457
Full Text :
https://doi.org/10.1093/eurheartj/ehae161