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Characterization of arsenic species by liquid sampling-atmospheric pressure glow discharge ionization mass spectrometry.

Authors :
Goodwin, Joseph
Kenneth Marcus, R.
McRae, Garnet
Sturgeon, Ralph E.
Mester, Zoltan
Source :
Analytical & Bioanalytical Chemistry; Jun2024, Vol. 416 Issue 15, p3585-3594, 10p
Publication Year :
2024

Abstract

A liquid sampling-atmospheric pressure glow discharge (LS-APGD) ionization source operating at a nominal power of 30 W and solution flow rate of 30 µL min<superscript>−1</superscript> and supported in a He sheath gas flow rate of 500 mL min<superscript>−1</superscript> was interfaced to an Orbitrap mass spectrometer and assessed for use in rapid identification of inorganic and organic arsenic species, including As(III), As(V), monomethylarsonic acid, dimethylarsinic acid, and arsenobetaine in a 2% (v/v) nitric acid medium. Mass spectral acquisition in low-resolution mode, using only the ion trap analyzer, provided detection of protonated molecular ions for AsBet (m/z 179), DMA (m/z 139), MMA (m/z 141), and As(V) (m/z 143). As(III) is oxidized to As(V), likely due to in-source processes. Typical fragmentation of these compounds resulted in the loss of either water or methyl groups, as appropriate, i.e., introducing DMA also generated ions corresponding to MMA and As(V) as dissociation products. Structure assignments were also confirmed by high-resolution Orbitrap measurements. Spectral fingerprint assignments were based on the introduction of solutions containing 5 µg mL<superscript>−1</superscript> of each arsenic compound. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16182642
Volume :
416
Issue :
15
Database :
Complementary Index
Journal :
Analytical & Bioanalytical Chemistry
Publication Type :
Academic Journal
Accession number :
177714251
Full Text :
https://doi.org/10.1007/s00216-024-05312-x